{"id":239774,"date":"2026-06-27T03:15:12","date_gmt":"2026-06-27T08:15:12","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/role-for-nanog-in-human-embryogenesis"},"modified":"2026-06-27T03:15:12","modified_gmt":"2026-06-27T08:15:12","slug":"role-for-nanog-in-human-embryogenesis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/role-for-nanog-in-human-embryogenesis","title":{"rendered":"Role for NANOG in human embryogenesis"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/role-for-nanog-in-human-embryogenesis.jpg\"><\/a><\/p>\n<p>New research has shown that a genome editing technique can be used to alter a single gene in human embryonic cells, enabling the study of very early human development in unparalleled detail.<\/p>\n<p>The technique, called base editing, is a more precise version of the genome editing technique CRISPR\/Cas9. It can change a single nucleotide base pair \u2014 the basic building block of DNA \u2014 within a human genome of approximately 3 billion base pairs.<\/p>\n<p>Using base editing, the researchers blocked a gene called NANOG in very early-stage human embryos, and found that the cells of the early embryo could not develop into more specialised pluripotent cells called the epiblast \u2014 which later form the body.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New research has shown that a genome editing technique can be used to alter a single gene in human embryonic cells, enabling the study of very early human development in unparalleled detail. The technique, called base editing, is a more precise version of the genome editing technique CRISPR\/Cas9. It can change a single nucleotide base [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-239774","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/239774","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=239774"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/239774\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=239774"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=239774"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=239774"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}