{"id":239744,"date":"2026-06-26T22:22:23","date_gmt":"2026-06-27T03:22:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/the-role-of-18ffdg-pet-ct-in-predicting-toxicity-in-patients-with-nhl-treated-with-car-t-a-systematic-review"},"modified":"2026-06-26T22:22:23","modified_gmt":"2026-06-27T03:22:23","slug":"the-role-of-18ffdg-pet-ct-in-predicting-toxicity-in-patients-with-nhl-treated-with-car-t-a-systematic-review","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/the-role-of-18ffdg-pet-ct-in-predicting-toxicity-in-patients-with-nhl-treated-with-car-t-a-systematic-review","title":{"rendered":"The Role of [18F]FDG PET\/CT in Predicting Toxicity in Patients with NHL Treated with CAR-T: A Systematic Review"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/the-role-of-18ffdg-pet-ct-in-predicting-toxicity-in-patients-with-nhl-treated-with-car-t-a-systematic-review2.jpg\"><\/a><\/p>\n<p>CAR-T-cell therapy, also referred to as chimeric antigen receptor T-cell therapy, is a novel method in the field of immunotherapy for the treatment of non-Hodgkin\u2019s lymphoma (NHL). In patients receiving CAR-T-cell therapy, fluorodeoxyglucose Positron Emission Tomography\/Computer Tomography ([18F]FDG PET\/CT) plays a critical role in tracking treatment response and evaluating the immunotherapy\u2019s overall efficacy. The aim of this study is to provide a systematic review of the literature on the studies aiming to assess and predict toxicity by means of [18F]FDG PET\/CT in patients with NHL receiving CAR-T-cell therapy. PubMed\/MEDLINE and Cochrane Central Register of Controlled Trials (CENTRAL) databases were interrogated by two investigators to seek studies involving the use of [18F]FDG PET\/CT in patients with lymphoma undergoing CAR-T-cell therapy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>CAR-T-cell therapy, also referred to as chimeric antigen receptor T-cell therapy, is a novel method in the field of immunotherapy for the treatment of non-Hodgkin\u2019s lymphoma (NHL). In patients receiving CAR-T-cell therapy, fluorodeoxyglucose Positron Emission Tomography\/Computer Tomography ([18F]FDG PET\/CT) plays a critical role in tracking treatment response and evaluating the immunotherapy\u2019s overall efficacy. The aim [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1523],"tags":[],"class_list":["post-239744","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-computing"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/239744","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=239744"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/239744\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=239744"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=239744"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=239744"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}