{"id":239683,"date":"2026-06-26T06:30:48","date_gmt":"2026-06-26T11:30:48","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/vulnerable-als-neurons-reveal-molecular-warning-signs-before-cell-death-begins"},"modified":"2026-06-26T06:30:48","modified_gmt":"2026-06-26T11:30:48","slug":"vulnerable-als-neurons-reveal-molecular-warning-signs-before-cell-death-begins","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/vulnerable-als-neurons-reveal-molecular-warning-signs-before-cell-death-begins","title":{"rendered":"Vulnerable ALS neurons reveal molecular warning signs before cell death begins"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/vulnerable-als-neurons-reveal-molecular-warning-signs-before-cell-death-begins2.jpg\"><\/a><\/p>\n<p>A new study from the Knight Initiative for Brain Resilience researchers may help explain an enduring mystery about amyotrophic lateral sclerosis (ALS): why the disease kills off some of the brain and spinal cord\u2019s movement-controlling neurons while others show greater resilience.<\/p>\n<p>As ALS progresses, more and more of those motor neurons degenerate and die. As a result, patients lose control of their bodies and become unable to breathe. Many people are diagnosed in middle to late adulthood, and most survive only three to five years after diagnosis.<\/p>\n<p>\u201cIt\u2019s a cruelly rapid disease,\u201d said Olivia Gautier, a postdoctoral scholar in the lab of Knight Initiative researcher Aaron Gitler, the Stanford Medicine Basic Science Professor and a professor of genetics at Stanford Medicine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study from the Knight Initiative for Brain Resilience researchers may help explain an enduring mystery about amyotrophic lateral sclerosis (ALS): why the disease kills off some of the brain and spinal cord\u2019s movement-controlling neurons while others show greater resilience. As ALS progresses, more and more of those motor neurons degenerate and die. As [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-239683","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/239683","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=239683"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/239683\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=239683"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=239683"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=239683"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}