{"id":238952,"date":"2026-06-14T02:06:04","date_gmt":"2026-06-14T07:06:04","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/sleep-and-exercise-may-curb-heart-risk-from-mutant-white-blood-cells"},"modified":"2026-06-14T02:06:04","modified_gmt":"2026-06-14T07:06:04","slug":"sleep-and-exercise-may-curb-heart-risk-from-mutant-white-blood-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/sleep-and-exercise-may-curb-heart-risk-from-mutant-white-blood-cells","title":{"rendered":"Sleep and exercise may curb heart risk from mutant white blood cells"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/sleep-and-exercise-may-curb-heart-risk-from-mutant-white-blood-cells.jpg\"><\/a><\/p>\n<p>Healthy sleep and regular exercise can work to counteract genetic mutations in white blood cells that are associated with cardiovascular disease and are most common among older people, Mount Sinai researchers have found. In a study <a href=\"https:\/\/www.nature.com\/articles\/s41586-026-10634-0\" target=\"_blank\">published<\/a> in <i>Nature<\/i>, the team reported for the first time that sufficient sleep and exercise can help reduce the cancer-like cell expansion and atherosclerotic risk linked to mutations that spontaneously occur in white blood cells.<\/p>\n<p>These mutations accumulate over our lifetimes and occur most often in hematopoietic stem cells, which are the cells in bone marrow that make blood cells, including macrophages and monocytes, immune cells that help defend the body. When these cells develop mutations, they start to proliferate, multiplying faster than they should, and become more inflammatory, irritating or damaging tissues in the body.<\/p>\n<p>This condition, known as <a href=\"https:\/\/medicalxpress.com\/news\/2024-01-exploring-clonal-hematopoiesis-impact-aging.html?utm_source=embeddings&utm_medium=related&utm_campaign=internal\" rel=\"related\">clonal hematopoiesis<\/a> (CH), is detectable in a quarter of people over age 70 and half of people over 80, the researchers say, though it is infrequent in young, healthy people.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Healthy sleep and regular exercise can work to counteract genetic mutations in white blood cells that are associated with cardiovascular disease and are most common among older people, Mount Sinai researchers have found. In a study published in Nature, the team reported for the first time that sufficient sleep and exercise can help reduce the [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,1495],"tags":[],"class_list":["post-238952","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/238952","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=238952"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/238952\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=238952"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=238952"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=238952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}