{"id":238672,"date":"2026-06-10T02:24:04","date_gmt":"2026-06-10T07:24:04","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/mapping-brain-network-changes-linked-to-bipolar-disorder-severity-and-treatment"},"modified":"2026-06-10T02:24:04","modified_gmt":"2026-06-10T07:24:04","slug":"mapping-brain-network-changes-linked-to-bipolar-disorder-severity-and-treatment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/mapping-brain-network-changes-linked-to-bipolar-disorder-severity-and-treatment","title":{"rendered":"Mapping brain network changes linked to bipolar disorder severity and treatment"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/iPN-1HNYwJM?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>New research from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has discovered subtle but widespread differences in the brain\u2019s communication networks in people with bipolar disorder, offering new insight into how illness severity and treatment may relate to brain wiring.<\/p>\n<p>Published in <i>Biological Psychiatry<\/i>, <a href=\"https:\/\/www.biologicalpsychiatryjournal.com\/article\/S0006-3223(26)01221-7\/fulltext\" target=\"_blank\">the study<\/a> was led by Leila Nabulsi, Ph.D., a senior research associate at the Stevens INI, together with Dara M. Cannon, Ph.D., professor at the University of Galway, Ireland. The team analyzed brain scans from 449 people with bipolar disorder and 510 healthy controls across 16 international research sites through the ENIGMA Bipolar Disorder Working Group.<\/p>\n<p>This work was made possible by ENIGMA, an international consortium founded and led in part by Paul M. Thompson, Ph.D., associate director of the Stevens INI. <a href=\"https:\/\/medicalxpress.com\/news\/2026-05-harnessing-brain-imaging-shift-mental.html?utm_source=embeddings&utm_medium=related&utm_campaign=internal\" rel=\"related\">ENIGMA<\/a> brings together researchers worldwide to pool their brain imaging and clinical data, allowing them to detect subtle patterns that would be difficult to identify in smaller studies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New research from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has discovered subtle but widespread differences in the brain\u2019s communication networks in people with bipolar disorder, offering new insight into how illness severity and treatment may relate to brain wiring. Published in Biological [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-238672","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/238672","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=238672"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/238672\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=238672"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=238672"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=238672"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}