{"id":238374,"date":"2026-06-04T22:13:24","date_gmt":"2026-06-05T03:13:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/alzheimers-gene-map-expands-to-91-loci-revealing-16-previously-unknown-risk-regions"},"modified":"2026-06-04T22:13:24","modified_gmt":"2026-06-05T03:13:24","slug":"alzheimers-gene-map-expands-to-91-loci-revealing-16-previously-unknown-risk-regions","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/alzheimers-gene-map-expands-to-91-loci-revealing-16-previously-unknown-risk-regions","title":{"rendered":"Alzheimer\u2019s gene map expands to 91 loci, revealing 16 previously unknown risk regions"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/alzheimers-gene-map-expands-to-91-loci-revealing-16-previously-unknown-risk-regions.jpg\"><\/a><\/p>\n<p>An international collaboration of genetic researchers has identified more than 90 genetic regions associated with the risk of Alzheimer\u2019s disease and related dementias. The large-scale meta-analysis reveals new biological insights into the disease, highlighting the important roles of immune processes, beta-amyloid and tau biology, and lipid metabolism.<\/p>\n<p>Alzheimer\u2019s disease is the most common cause of dementia worldwide, and its development is influenced by a complex interplay of genetic and environmental factors. Understanding the genetic architecture of the disease is essential for improving diagnosis, risk prediction, and the development of targeted therapies.<\/p>\n<p>In this study, researchers combined genome-wide association data from nearly a million individuals of European ancestry, including over 128,000 Alzheimer\u2019s disease cases and nearly 850,000 controls.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An international collaboration of genetic researchers has identified more than 90 genetic regions associated with the risk of Alzheimer\u2019s disease and related dementias. The large-scale meta-analysis reveals new biological insights into the disease, highlighting the important roles of immune processes, beta-amyloid and tau biology, and lipid metabolism. Alzheimer\u2019s disease is the most common cause of [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-238374","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/238374","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=238374"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/238374\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=238374"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=238374"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=238374"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}