{"id":238182,"date":"2026-06-02T06:15:47","date_gmt":"2026-06-02T11:15:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/06\/childrens-brain-tumors-may-spread-faster-when-microglia-build-invasion-friendly-scaffolding"},"modified":"2026-06-02T06:15:47","modified_gmt":"2026-06-02T11:15:47","slug":"childrens-brain-tumors-may-spread-faster-when-microglia-build-invasion-friendly-scaffolding","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/06\/childrens-brain-tumors-may-spread-faster-when-microglia-build-invasion-friendly-scaffolding","title":{"rendered":"Children\u2019s brain tumors may spread faster when microglia build invasion-friendly scaffolding"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/childrens-brain-tumors-may-spread-faster-when-microglia-build-invasion-friendly-scaffolding2.jpg\"><\/a><\/p>\n<p>Researchers at the Institute of Environmental Medicine (IMM), Karolinska Institutet, have identified a possible mechanism behind the spread of the aggressive brain tumor diffuse midline glioma. The study shows that the brain\u2019s own immune cells, microglia, may contribute to the tumor\u2019s invasive capacity by producing the protein fibronectin. The results are <a href=\"https:\/\/www.nature.com\/articles\/s41419-026-08891-y\" target=\"_blank\">published<\/a> in the journal Cell Death &amp; Disease.<\/p>\n<p>Diffuse midline glioma (DMG), also known as diffuse intrinsic pontine glioma (DIPG), is a rare but highly aggressive brain tumor that primarily affects children. There is currently no effective treatment, and the prognosis is very poor.<\/p>\n<p>In the present study, the researchers investigated how microglia\u2014the brain\u2019s immune cells\u2014are affected by tumor cells and what role they play in disease progression.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the Institute of Environmental Medicine (IMM), Karolinska Institutet, have identified a possible mechanism behind the spread of the aggressive brain tumor diffuse midline glioma. The study shows that the brain\u2019s own immune cells, microglia, may contribute to the tumor\u2019s invasive capacity by producing the protein fibronectin. The results are published in the journal [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-238182","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/238182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=238182"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/238182\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=238182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=238182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=238182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}