{"id":237685,"date":"2026-05-24T14:09:44","date_gmt":"2026-05-24T19:09:44","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/05\/human-monoclonal-antibodies-that-target-the-sftsv-glycoprotein-gn-head-from-four-neutralizing-epitope-groups"},"modified":"2026-05-24T14:09:44","modified_gmt":"2026-05-24T19:09:44","slug":"human-monoclonal-antibodies-that-target-the-sftsv-glycoprotein-gn-head-from-four-neutralizing-epitope-groups","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/05\/human-monoclonal-antibodies-that-target-the-sftsv-glycoprotein-gn-head-from-four-neutralizing-epitope-groups","title":{"rendered":"Human monoclonal antibodies that target the SFTSV glycoprotein Gn head from four neutralizing epitope groups"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/human-monoclonal-antibodies-that-target-the-sftsv-glycoprotein-gn-head-from-four-neutralizing-epitope-groups2.jpg\"><\/a><\/p>\n<p>Wang et al. report that Gn-specific mAbs from SFTS survivors exhibit broad and potent neutralization, with two providing complete protection in a lethal mouse model. This work maps the Gn antigenic landscape and establishes a deep mutational scanning platform coupled with structural validation for bunyavirus antibody discovery.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wang et al. report that Gn-specific mAbs from SFTS survivors exhibit broad and potent neutralization, with two providing complete protection in a lethal mouse model. This work maps the Gn antigenic landscape and establishes a deep mutational scanning platform coupled with structural validation for bunyavirus antibody discovery.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-237685","post","type-post","status-publish","format-standard","hentry","category-mapping"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/237685","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=237685"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/237685\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=237685"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=237685"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=237685"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}