{"id":237411,"date":"2026-05-19T19:18:41","date_gmt":"2026-05-20T00:18:41","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/05\/this-gene-is-linked-to-lower-alzheimers-risk-and-we-may-finally-know-why"},"modified":"2026-05-19T19:18:41","modified_gmt":"2026-05-20T00:18:41","slug":"this-gene-is-linked-to-lower-alzheimers-risk-and-we-may-finally-know-why","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/05\/this-gene-is-linked-to-lower-alzheimers-risk-and-we-may-finally-know-why","title":{"rendered":"This Gene Is Linked to Lower Alzheimer\u2019s Risk \u2014 And We May Finally Know Why"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/this-gene-is-linked-to-lower-alzheimers-risk-and-we-may-finally-know-why.jpg\"><\/a><\/p>\n<p>There\u2019s something special about the <em>APOE2<\/em> variant of the <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/alzheimers-disease\/in-depth\/alzheimers-genes\/art-20046552\"><em>APOE <\/em>(apolipoprotein E) gene<\/a>: People who carry it tend <a href=\"https:\/\/www.sciencealert.com\/one-critical-factor-predicts-longevity-better-than-diet-or-exercise-study-finds\">to live longer<\/a>, and they have a lower risk of developing <a href=\"https:\/\/www.sciencealert.com\/go\/IaO\" rel=\"nofollow\" target=\"_self\">Alzheimer\u2019s<\/a> disease.<\/p>\n<p>Scientists are still trying to figure out why, and now, they have a new lead.<\/p>\n<p>A team led by researchers at the Buck Institute for Research on Aging in the US set out to answer that question using human stem cell-derived neurons and mouse studies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>There\u2019s something special about the APOE2 variant of the APOE (apolipoprotein E) gene: People who carry it tend to live longer, and they have a lower risk of developing Alzheimer\u2019s disease. Scientists are still trying to figure out why, and now, they have a new lead. A team led by researchers at the Buck Institute [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-237411","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/237411","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=237411"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/237411\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=237411"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=237411"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=237411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}