{"id":237336,"date":"2026-05-18T06:04:46","date_gmt":"2026-05-18T11:04:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/05\/small-study-shows-one-time-cell-therapy-can-control-hiv-infection"},"modified":"2026-05-18T06:04:46","modified_gmt":"2026-05-18T11:04:46","slug":"small-study-shows-one-time-cell-therapy-can-control-hiv-infection","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/05\/small-study-shows-one-time-cell-therapy-can-control-hiv-infection","title":{"rendered":"Small Study Shows One-time Cell Therapy Can Control HIV Infection"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/small-study-shows-one-time-cell-therapy-can-control-hiv-infection.jpg\"><\/a><\/p>\n<p>Unlike previous HIV \u201ccures\u201d involving cancer patients given bone marrow stem cells from a donor with a rare genetic mutation that resists HIV infection, researchers said CAR-T could be used by a much broader patient population. The Phase 1 trial involved CAR-T, a one-time therapy in which a patient\u2019s T-cells are extracted, altered and multiplied in a lab and infused back into \u2060their body. In this case, the CAR-T targeted the CD4 and CCR5 binding sites of the HIV.<\/p>\n<p>Of three trial patients \u200ctreated with a standard CAR-T dose, researchers said two maintained undetectable to \u200cvery low levels of HIV after stopping antiretroviral therapy \u2014 one for over two years so far and another for nearly a year. \u201cThe two that have \u200cbeen off (HIV drugs) the longest and doing well were importantly diagnosed pretty quickly and put on therapy pretty quickly,\u201d said Dr. Steven Deeks, professor of medicine at the University of California, San Francisco and the study\u2019s lead investigator.<\/p>\n<p>Currently, CAR-T \u200ctreatments are available for several types of blood cancer, and are being developed for autoimmune diseases like lupus and scleroderma. Tap the link to learn more about the recent study.<\/p>\n<hr>\n<p>Re-engineering an HIV patient\u2019s own immune cells to find and destroy the virus succeeded in controlling the infection in a small first-in-human study, but researchers said work is needed to confirm \u2060the findings and determine which patients are most likely to benefit.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Unlike previous HIV \u201ccures\u201d involving cancer patients given bone marrow stem cells from a donor with a rare genetic mutation that resists HIV infection, researchers said CAR-T could be used by a much broader patient population. The Phase 1 trial involved CAR-T, a one-time therapy in which a patient\u2019s T-cells are extracted, altered and multiplied [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-237336","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/237336","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=237336"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/237336\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=237336"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=237336"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=237336"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}