{"id":236893,"date":"2026-05-11T02:11:02","date_gmt":"2026-05-11T07:11:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/05\/a-protein-directs-neuronal-migration-in-the-embryonic-brain"},"modified":"2026-05-11T02:11:02","modified_gmt":"2026-05-11T07:11:02","slug":"a-protein-directs-neuronal-migration-in-the-embryonic-brain","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/05\/a-protein-directs-neuronal-migration-in-the-embryonic-brain","title":{"rendered":"A protein directs neuronal migration in the embryonic brain"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-protein-directs-neuronal-migration-in-the-embryonic-brain2.jpg\"><\/a><\/p>\n<p>During brain development, neurons can regulate their movement until they reach their final destination thanks to a \u201cmolecular switch\u201d involving the protein Teneurin 4 (Ten4). This protein can guide neuronal migration through mutually exclusive molecular pathways and determine the direction of nerve cells.<\/p>\n<p>The discovery, published in the journal <a href=\"https:\/\/www.nature.com\/articles\/s41467-026-71619-1\">Nature Communications<\/a>, improves our understanding of the molecular mechanisms that control neuronal migration and offers new insights into how the brain develops at the molecular level.<\/p>\n<p>The study combines advanced techniques \u2014 structural protein studies, gene editing in animal models and super-resolution microscopy \u2014 to broaden our understanding of the origins of neurodevelopmental disorders and psychiatric or neurological conditions \u2014schizophrenia, epilepsy, autism, bipolar disorder, etc. \u2014 which may be linked to errors in neuronal migration.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>During brain development, neurons can regulate their movement until they reach their final destination thanks to a \u201cmolecular switch\u201d involving the protein Teneurin 4 (Ten4). This protein can guide neuronal migration through mutually exclusive molecular pathways and determine the direction of nerve cells. The discovery, published in the journal Nature Communications, improves our understanding of [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,47],"tags":[],"class_list":["post-236893","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/236893","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=236893"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/236893\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=236893"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=236893"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=236893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}