{"id":236327,"date":"2026-05-01T19:20:46","date_gmt":"2026-05-02T00:20:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/05\/clinical-impact-of-cardiac-magnetic-resonance-imaging-in-myocardial-infarction-with-non-obstructive-coronary-arteries-a-prospective-multicentre-cohort-study"},"modified":"2026-05-01T19:20:46","modified_gmt":"2026-05-02T00:20:46","slug":"clinical-impact-of-cardiac-magnetic-resonance-imaging-in-myocardial-infarction-with-non-obstructive-coronary-arteries-a-prospective-multicentre-cohort-study","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/05\/clinical-impact-of-cardiac-magnetic-resonance-imaging-in-myocardial-infarction-with-non-obstructive-coronary-arteries-a-prospective-multicentre-cohort-study","title":{"rendered":"Clinical impact of cardiac magnetic resonance imaging in myocardial infarction with non-obstructive coronary arteries: a prospective multicentre cohort study"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/clinical-impact-of-cardiac-magnetic-resonance-imaging-in-myocardial-infarction-with-non-obstructive-coronary-arteries-a-prospective-multicentre-cohort-study2.jpg\"><\/a><\/p>\n<p><strong>Background<\/strong> Cardiac magnetic resonance (CMR) may radiologically identify or confirm underlying pathophysiologies in myocardial infarction with non-obstructive coronary arteries (MINOCA), however, there are scant prospective data evaluating the impact on routine clinical care.<\/p>\n<p><strong>Methods<\/strong> In a multicentre international cohort study of MINOCA, clinical diagnosis, diagnostic certainty and intended clinical management were prospectively determined before and again after CMR. The primary outcome was a composite of change in clinical diagnosis and\/or management. Secondary outcomes were individual components of the primary outcome, change in diagnostic certainty and number-needed-to-test for deprescription of dual antiplatelet therapy (DAPT). Predictors of the primary outcome were evaluated by multivariable logistic regression analysis.<\/p>\n<p>Results In 320 patients, CMR was associated with change in diagnosis and\/or management in 63% (95% CI 57% to 68%, p0.001) and significantly increased diagnostic certainty (8\u00f710 post-CMR (5\u20139) vs 6\/10 pre-CMR (4\u20137), p0.0001). Relevant predictors of the primary outcome on multivariable analysis were early CMR (\u226414 days), absence of atheroma on coronary angiography and significant pre-CMR diagnostic uncertainty (\u22645\/10); CMR changed diagnosis and\/or management in 80% of individuals with all three predictors versus 40% in those with none. In individuals where treating physicians initially chose to prescribe DAPT despite no obstructive culprit lesion, number-needed-to-test by CMR for DAPT deprescription was 3.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background Cardiac magnetic resonance (CMR) may radiologically identify or confirm underlying pathophysiologies in myocardial infarction with non-obstructive coronary arteries (MINOCA), however, there are scant prospective data evaluating the impact on routine clinical care. Methods In a multicentre international cohort study of MINOCA, clinical diagnosis, diagnostic certainty and intended clinical management were prospectively determined before and [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-236327","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/236327","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=236327"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/236327\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=236327"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=236327"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=236327"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}