{"id":236055,"date":"2026-04-28T02:21:14","date_gmt":"2026-04-28T07:21:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/il-4-treatment-induces-apoptosis-of-blood-monocytes-and-proliferation-of-recruited-injury-associated-macrophages-to-resolve-liver-injury"},"modified":"2026-04-28T02:21:14","modified_gmt":"2026-04-28T07:21:14","slug":"il-4-treatment-induces-apoptosis-of-blood-monocytes-and-proliferation-of-recruited-injury-associated-macrophages-to-resolve-liver-injury","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/il-4-treatment-induces-apoptosis-of-blood-monocytes-and-proliferation-of-recruited-injury-associated-macrophages-to-resolve-liver-injury","title":{"rendered":"IL-4 treatment induces apoptosis of blood monocytes and proliferation of recruited injury-associated macrophages to resolve liver injury"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/il-4-treatment-induces-apoptosis-of-blood-monocytes-and-proliferation-of-recruited-injury-associated-macrophages-to-resolve-liver-injury2.jpg\"><\/a><\/p>\n<p>Pathways that favor the balance of immune cells toward those with healing potential offer therapeutic promise following injury. Here, Lynch at al. show that treatment with IL-4 expands pro-reparative macrophages through proliferation while driving concurrent death of their more inflammatory precursors, resulting in accelerated hepatic repair following acute liver injury.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pathways that favor the balance of immune cells toward those with healing potential offer therapeutic promise following injury. Here, Lynch at al. show that treatment with IL-4 expands pro-reparative macrophages through proliferation while driving concurrent death of their more inflammatory precursors, resulting in accelerated hepatic repair following acute liver injury.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-236055","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/236055","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=236055"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/236055\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=236055"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=236055"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=236055"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}