{"id":236044,"date":"2026-04-27T22:52:20","date_gmt":"2026-04-28T03:52:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/the-ear-as-a-therapeutic-gateway-to-the-vagus-nerve"},"modified":"2026-04-27T22:52:20","modified_gmt":"2026-04-28T03:52:20","slug":"the-ear-as-a-therapeutic-gateway-to-the-vagus-nerve","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/the-ear-as-a-therapeutic-gateway-to-the-vagus-nerve","title":{"rendered":"The Ear as a Therapeutic Gateway to the Vagus Nerve"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/the-ear-as-a-therapeutic-gateway-to-the-vagus-nerve.jpg\"><\/a><\/p>\n<p>B cell-intrinsic type I interferon signaling contributes to defective antibody responses to a model antigen during persistent LCMV infection.<\/p>\n<hr>\n<p>During persistent LCMV infection, Laulh\u00e9 et al. reveal that B cell-intrinsic type I interferon (IFN-I) signaling drives defective affinity maturation. Although IFN-I acts directly within B cells, its absence alone fails to restore normal humoral responses, indicating that additional extrinsic mechanisms cooperate to sustain dysfunction.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>B cell-intrinsic type I interferon signaling contributes to defective antibody responses to a model antigen during persistent LCMV infection. During persistent LCMV infection, Laulh\u00e9 et al. reveal that B cell-intrinsic type I interferon (IFN-I) signaling drives defective affinity maturation. Although IFN-I acts directly within B cells, its absence alone fails to restore normal humoral responses, [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-236044","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/236044","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=236044"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/236044\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=236044"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=236044"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=236044"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}