{"id":235837,"date":"2026-04-24T07:21:26","date_gmt":"2026-04-24T12:21:26","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/identifying-high-risk-smoldering-multiple-myeloma-for-early-intervention"},"modified":"2026-04-24T07:21:26","modified_gmt":"2026-04-24T12:21:26","slug":"identifying-high-risk-smoldering-multiple-myeloma-for-early-intervention","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/identifying-high-risk-smoldering-multiple-myeloma-for-early-intervention","title":{"rendered":"Identifying High-Risk Smoldering Multiple Myeloma for Early Intervention"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/identifying-high-risk-smoldering-multiple-myeloma-for-early-intervention.png\"><\/a><\/p>\n<p>In a cohort study comparing high-risk definitions for smoldering multiple myeloma (#SMM), the AQUILA trial criteria was assessed against the 2\/20\/20 risk model.<\/p>\n<p>The AQUILA criteria classified approximately 3 times more individuals as high-risk versus the 2\/20\/20 model, but included a substantial group with lower progression risk.<\/p>\n<p>The 2\/20\/20 model more precisely identified a smaller group of individuals with higher risk of progression, supporting its use to target early intervention for those most likely to benefit.<\/p>\n<hr>\n<p>This cohort study compares the AQUILA trial inclusion criteria and the 2\/20\/20 risk stratification model definitions for identifying individuals with smoldering multiple myeloma at high risk of progression.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a cohort study comparing high-risk definitions for smoldering multiple myeloma (#SMM), the AQUILA trial criteria was assessed against the 2\/20\/20 risk model. The AQUILA criteria classified approximately 3 times more individuals as high-risk versus the 2\/20\/20 model, but included a substantial group with lower progression risk. The 2\/20\/20 model more precisely identified a smaller [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-235837","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235837","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=235837"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235837\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=235837"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=235837"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=235837"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}