{"id":235650,"date":"2026-04-21T18:09:23","date_gmt":"2026-04-21T23:09:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/mechanical-thrombectomy-and-final-infarct-volume-in-patients-with-stroke"},"modified":"2026-04-21T18:09:23","modified_gmt":"2026-04-21T23:09:23","slug":"mechanical-thrombectomy-and-final-infarct-volume-in-patients-with-stroke","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/mechanical-thrombectomy-and-final-infarct-volume-in-patients-with-stroke","title":{"rendered":"Mechanical Thrombectomy and Final Infarct Volume in Patients With Stroke"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mechanical-thrombectomy-and-final-infarct-volume-in-patients-with-stroke2.png\"><\/a><\/p>\n<p>In <i>Stroke<\/i> due to medium or distal vessel occlusion, endovascular treatment plus best medical treatment preserved more brain tissue and was linked to improved imaging outcomes and better clinical recovery compared with medical treatment alone.<\/p>\n<hr>\n<p>Interventions EVT plus BMT compared with BMT alone.<\/p>\n<p>Main Outcomes and Measures Primary outcome was calculated as the difference in volume of tissue at risk and the final infarct volume divided by the tissue at risk (change in Vrel). We defined a Vrel of 0.8 or greater as a good imaging outcome, meaning that at least 80% of the brain tissue initially at risk was not infarcted at 24 hours. Additionally, the association between brain tissue preserved and clinical outcome at 90 days was investigated.<\/p>\n<p><strong>Results<\/strong> From the 447 patients (252 [56.4%] male; median [IQR] age, 77.0 [68.0\u201384.0] years) included in this secondary analysis, 226 received EVT plus BMT and 221 received BMT alone. Median (IQR) time of the follow-up imaging was 22.9 (19.2\u221225.5) hours. Median (IQR) Time to maximum less than 6 seconds (Tmax6) volume was 34.0 (20.0\u221250.0) mL. Median follow-up infarct volume was 7.0 (1.0\u221222.9) mL. The median (IQR) change in absolute volume in the EVT plus BMT group was 23.6 (5.7\u221238.9) mL and 14.8 (0\u221230.3) mL in the BMT group. Median (IQR) change in Vrel was 0.8 (0.2\u22121.0) in the EVT plus BMT group and 0.6 (0\u22120.9) in the BMT group. Odds for reaching a change in Vrel of 0.8 or greater were higher in the EVT plus BMT group compared with BMT (adjusted odds ratio [aOR], 1.6; 95% CI, 1.1\u22122.3) and with successful reperfusion compared with no successful reperfusion (aOR, 2.5; 95% CI, 1.3\u22124.8). Patients with a change in Vrel of 0.8 or greater had a better clinical outcome at 90 days.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In Stroke due to medium or distal vessel occlusion, endovascular treatment plus best medical treatment preserved more brain tissue and was linked to improved imaging outcomes and better clinical recovery compared with medical treatment alone. Interventions EVT plus BMT compared with BMT alone. Main Outcomes and Measures Primary outcome was calculated as the difference in [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-235650","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235650","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=235650"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235650\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=235650"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=235650"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=235650"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}