{"id":235631,"date":"2026-04-20T23:00:00","date_gmt":"2026-04-21T04:00:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/systematic-discovery-of-pro-and-anti-hiv-host-factors-in-primary-human-cd4-t-cells"},"modified":"2026-04-20T23:00:00","modified_gmt":"2026-04-21T04:00:00","slug":"systematic-discovery-of-pro-and-anti-hiv-host-factors-in-primary-human-cd4-t-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/systematic-discovery-of-pro-and-anti-hiv-host-factors-in-primary-human-cd4-t-cells","title":{"rendered":"Systematic discovery of pro- and anti-HIV host factors in primary human CD4+ T cells"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/systematic-discovery-of-pro-and-anti-hiv-host-factors-in-primary-human-cd4-t-cells2.jpg\"><\/a><\/p>\n<p>Now online! Genome-wide CRISPR activation and knockout screens in primary human CD4+ T cells systematically identify host proviral and antiviral factors modulating HIV infection, including the strongly antiviral factor PPID, which is shown to bind HIV capsid and reduce its nuclear import.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Now online! Genome-wide CRISPR activation and knockout screens in primary human CD4+ T cells systematically identify host proviral and antiviral factors modulating HIV infection, including the strongly antiviral factor PPID, which is shown to bind HIV capsid and reduce its nuclear import.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-235631","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235631","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=235631"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235631\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=235631"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=235631"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=235631"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}