{"id":235602,"date":"2026-04-20T22:30:11","date_gmt":"2026-04-21T03:30:11","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/each-protein-in-the-epigenome-produces-a-different-pattern-of-gene-expression-study-finds"},"modified":"2026-04-20T22:30:11","modified_gmt":"2026-04-21T03:30:11","slug":"each-protein-in-the-epigenome-produces-a-different-pattern-of-gene-expression-study-finds","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/each-protein-in-the-epigenome-produces-a-different-pattern-of-gene-expression-study-finds","title":{"rendered":"Each protein in the epigenome produces a different pattern of gene expression, study finds"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/each-protein-in-the-epigenome-produces-a-different-pattern-of-gene-expression-study-finds2.jpg\"><\/a><\/p>\n<p>A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off. Essentially, each type of protein that interacts with a gene produces different behaviors\u2014a finding with ramifications for everything from biomedical therapeutics to biological computing. A paper on the study, \u201cEpigenome Regulators Imbue a Single Eukaryotic Promoter with Diverse Gene Expression Dynamics,\u201d is <a href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004226011806\" target=\"_blank\">published<\/a> in the journal iScience.<\/p>\n<p>At issue are \u201cepigenome regulators.\u201d Every organism\u2019s genome is made up of DNA. But that DNA is bound up with many different proteins into very compact structures. The proteins that are bound to the DNA are called the epigenome, and they control which parts of the DNA get expressed. Your <a href=\"https:\/\/phys.org\/news\/2023-12-mathematical-language-biological-networks.html?utm_source=embeddings&utm_medium=related&utm_campaign=internal\" rel=\"related\">blood cells<\/a>, nerve cells, and skin cells all have the same DNA, but perform very different functions. That\u2019s because different parts of the DNA sequence are being expressed in each cell\u2014and that is largely controlled by which proteins are bound to different parts of the DNA in each cell.<\/p>\n<p>\u201cWe already knew that the proteins in the epigenome control the way DNA is expressed,\u201d says Albert Keung, corresponding author of the study and an associate professor of chemical and biomolecular engineering at North Carolina State University. \u201cOur goal here was to look at a single gene and quantify the full range of ways that the gene could be expressed by different proteins.\u201d Keung is the Goodnight Distinguished Scholar in Innovation in Biotechnology and Biomolecular Engineering and director of biotechnology programs in NC State\u2019s Integrative Sciences Initiative.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off. Essentially, each type of protein that interacts with a gene produces different behaviors\u2014a finding with ramifications for everything from biomedical therapeutics to biological computing. A paper on the study, [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,19,1523],"tags":[],"class_list":["post-235602","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-chemistry","category-computing"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235602","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=235602"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235602\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=235602"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=235602"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=235602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}