{"id":235219,"date":"2026-04-14T22:55:43","date_gmt":"2026-04-15T03:55:43","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/immunogenic-xaps-are-released-by-netosis-and-associated-with-high-risk-vasculopathy-in-patients-with-ssc"},"modified":"2026-04-14T22:55:43","modified_gmt":"2026-04-15T03:55:43","slug":"immunogenic-xaps-are-released-by-netosis-and-associated-with-high-risk-vasculopathy-in-patients-with-ssc","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/immunogenic-xaps-are-released-by-netosis-and-associated-with-high-risk-vasculopathy-in-patients-with-ssc","title":{"rendered":"Immunogenic XAPs are released by NETosis and associated with high-risk vasculopathy in patients with SSc"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/immunogenic-xaps-are-released-by-netosis-and-associated-with-high-risk-vasculopathy-in-patients-with-ssc.jpg\"><\/a><\/p>\n<p>AutoimmuneDiseases affect nearly 50 million Americans, and 4 out of 5 patients are women.<\/p>\n<p><a href=\"https:\/\/doi.org\/10.1172\/JCI198291\">https:\/\/doi.org\/10.1172\/JCI198291<\/a> In this Research Letter, Howard Y. Chang &amp; team show novel autoantibodies target hotspots on the XIST ribonucleoprotein complex in female-biased autoimmune diseases.<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Department of Dermatology and.<\/p>\n<p><sup>2<\/sup>Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.<\/p>\n<p><sup>3<\/sup>RNA Medicine Program, Stanford University, Stanford, California, USA.<\/p>\n<p><sup>4<\/sup>Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2026\/04\/immunogenic-xaps-are-released-by-netosis-and-associated-with-high-risk-vasculopathy-in-patients-with-ssc\">Continue reading \u201cImmunogenic XAPs are released by NETosis and associated with high-risk vasculopathy in patients with SSc\u201d | &gt;<\/a><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"<p>AutoimmuneDiseases affect nearly 50 million Americans, and 4 out of 5 patients are women. https:\/\/doi.org\/10.1172\/JCI198291 In this Research Letter, Howard Y. Chang &amp; team show novel autoantibodies target hotspots on the XIST ribonucleoprotein complex in female-biased autoimmune diseases. 1Department of Dermatology and. 2Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-235219","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235219","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=235219"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235219\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=235219"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=235219"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=235219"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}