{"id":235015,"date":"2026-04-11T10:04:36","date_gmt":"2026-04-11T15:04:36","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/enucleated-cells-with-nectin-1-overexpression-capture-hsv-1-and-promote-viral-elimination-for-herpes-simplex-encephalitis-therapy"},"modified":"2026-04-11T10:04:36","modified_gmt":"2026-04-11T15:04:36","slug":"enucleated-cells-with-nectin-1-overexpression-capture-hsv-1-and-promote-viral-elimination-for-herpes-simplex-encephalitis-therapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/enucleated-cells-with-nectin-1-overexpression-capture-hsv-1-and-promote-viral-elimination-for-herpes-simplex-encephalitis-therapy","title":{"rendered":"Enucleated cells with Nectin-1 overexpression capture HSV-1 and promote viral elimination for herpes simplex encephalitis therapy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/enucleated-cells-with-nectin-1-overexpression-capture-hsv-1-and-promote-viral-elimination-for-herpes-simplex-encephalitis-therapy.jpg\"><\/a><\/p>\n<p>Zhou et al. describe an antiviral strategy for herpes simplex encephalitis that employs enucleated MSCs overexpressing Nectin-1 as decoys. This strategy effectively sequesters the virus and prevents its intracellular replication. Ultimately, they undergo programmed apoptosis, thereby facilitating macrophage-mediated clearance. This strategy offers a therapeutic approach for refractory viral infections.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zhou et al. describe an antiviral strategy for herpes simplex encephalitis that employs enucleated MSCs overexpressing Nectin-1 as decoys. This strategy effectively sequesters the virus and prevents its intracellular replication. Ultimately, they undergo programmed apoptosis, thereby facilitating macrophage-mediated clearance. This strategy offers a therapeutic approach for refractory viral infections.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-235015","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235015","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=235015"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/235015\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=235015"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=235015"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=235015"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}