{"id":234915,"date":"2026-04-10T04:00:28","date_gmt":"2026-04-10T09:00:28","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/how-does-the-most-common-cause-of-alternating-hemiplegia-of-childhood-ahc-lead-to-abnormal-repolarization-and-arrhythmogenesis"},"modified":"2026-04-10T04:00:28","modified_gmt":"2026-04-10T09:00:28","slug":"how-does-the-most-common-cause-of-alternating-hemiplegia-of-childhood-ahc-lead-to-abnormal-repolarization-and-arrhythmogenesis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/how-does-the-most-common-cause-of-alternating-hemiplegia-of-childhood-ahc-lead-to-abnormal-repolarization-and-arrhythmogenesis","title":{"rendered":"How does the most common cause of Alternating Hemiplegia of Childhood (AHC) lead to abnormal repolarization and arrhythmogenesis?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/how-does-the-most-common-cause-of-alternating-hemiplegia-of-childhood-ahc-lead-to-abnormal-repolarization-and-arrhythmogenesis2.jpg\"><\/a><\/p>\n<p>Andrew P. Landstrom &amp; team propose a Ca2+-mediated mechanism in <i>ATP1A3<\/i>-D801N carriers &amp; identify NCX1 as a possible therapeutic target.<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Department of Cell Biology and.<\/p>\n<p><sup>2<\/sup>Department of Pediatrics, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA.<\/p>\n<p><sup>3<\/sup>Department of Biomedical Engineering and.<\/p>\n<p><sup>4<\/sup>Division of Pediatric Neurology and Developmental Medicine, Department of Pediatrics, Duke University, Durham, North Carolina, USA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Andrew P. Landstrom &amp; team propose a Ca2+-mediated mechanism in ATP1A3-D801N carriers &amp; identify NCX1 as a possible therapeutic target. 1Department of Cell Biology and. 2Department of Pediatrics, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA. 3Department of Biomedical Engineering and. 4Division of Pediatric Neurology and Developmental Medicine, Department of Pediatrics, [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,38],"tags":[],"class_list":["post-234915","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-engineering"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=234915"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234915\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=234915"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=234915"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=234915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}