{"id":234797,"date":"2026-04-07T22:39:01","date_gmt":"2026-04-08T03:39:01","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/abstract-detailing-the-effects-of-a-new-therapeutic-tuberculosis-vaccine"},"modified":"2026-04-07T22:39:01","modified_gmt":"2026-04-08T03:39:01","slug":"abstract-detailing-the-effects-of-a-new-therapeutic-tuberculosis-vaccine","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/abstract-detailing-the-effects-of-a-new-therapeutic-tuberculosis-vaccine","title":{"rendered":"Abstract: Detailing the effects of a new therapeutic tuberculosis vaccine!"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/abstract121.jpg\"><\/a><\/p>\n<p><a href=\"https:\/\/doi.org\/10.1172\/JCI196648\">https:\/\/doi.org\/10.1172\/JCI196648<\/a> In this Research Article, Styliani Karanika &amp; team report on an intranasal DNA vaccine that accelerates TB cure and achieves better outcomes than standard or drug-resistant regimens alone in preclinical models.<\/p>\n<p>The figure shows mouse lungs with therapeutic intranasal <i><i>Mip3a\/relMt <\/i>b<\/i> fusion immunization, revealing local dendritic cell infiltration and enhanced colocalization with T cells.<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Center for Tuberculosis Research, Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<\/p>\n<p><sup>2<\/sup>W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.<\/p>\n<p><sup>3<\/sup>Division of Hematological Malignancies, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University Hospital, Baltimore, Maryland, USA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>https:\/\/doi.org\/10.1172\/JCI196648 In this Research Article, Styliani Karanika &amp; team report on an intranasal DNA vaccine that accelerates TB cure and achieves better outcomes than standard or drug-resistant regimens alone in preclinical models. The figure shows mouse lungs with therapeutic intranasal Mip3a\/relMt b fusion immunization, revealing local dendritic cell infiltration and enhanced colocalization with T cells. [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-234797","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234797","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=234797"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234797\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=234797"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=234797"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=234797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}