{"id":234700,"date":"2026-04-06T22:12:15","date_gmt":"2026-04-07T03:12:15","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/the-protein-rab5if-promotes-bdnf-signaling-by-stimulating-the-sumoylation-of-g%ce%b1i1-3-to-reduce-depressive-like-behaviors-in-mice"},"modified":"2026-04-06T22:12:15","modified_gmt":"2026-04-07T03:12:15","slug":"the-protein-rab5if-promotes-bdnf-signaling-by-stimulating-the-sumoylation-of-g%ce%b1i1-3-to-reduce-depressive-like-behaviors-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/the-protein-rab5if-promotes-bdnf-signaling-by-stimulating-the-sumoylation-of-g%ce%b1i1-3-to-reduce-depressive-like-behaviors-in-mice","title":{"rendered":"The protein RAB5IF promotes BDNF signaling by stimulating the SUMOylation of G\u03b1i1\/3 to reduce depressive-like behaviors in mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/the-protein-rab5if-promotes-bdnf-signaling-by-stimulating-the-sumoylation-of-gceb1i1-3-to-reduce-depressive-like-behaviors-in-mice.jpg\"><\/a><\/p>\n<p>A mitochondrial protein indirectly supports antidepressant BDNF signaling in the brain.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A mitochondrial protein indirectly supports antidepressant BDNF signaling in the brain.<\/p>\n","protected":false},"author":715,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-234700","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234700","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/715"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=234700"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234700\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=234700"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=234700"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=234700"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}