{"id":234440,"date":"2026-04-02T03:04:09","date_gmt":"2026-04-02T08:04:09","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/04\/advancing-the-manufacture-of-patient-accessible-cell-and-gene-therapies-at-place-of-care"},"modified":"2026-04-02T03:04:09","modified_gmt":"2026-04-02T08:04:09","slug":"advancing-the-manufacture-of-patient-accessible-cell-and-gene-therapies-at-place-of-care","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/04\/advancing-the-manufacture-of-patient-accessible-cell-and-gene-therapies-at-place-of-care","title":{"rendered":"Advancing the Manufacture of Patient Accessible Cell and Gene Therapies at Place-of-Care"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/advancing-the-manufacture-of-patient-accessible-cell-and-gene-therapies-at-place-of-care.jpg\"><\/a><\/p>\n<p>A partnership involving a medical school, a non-profit organization, and a biotech company have formed a partnership for the development and manufacture of an accessible and commercially viable hematopoietic stem cell (HSC) manufacturing platform for diseases like sickle cell disease (SCD). The alliance combines Trenchant BioSystems\u2019 technology for automating patient-specific cell and gene therapy (CGT) processes, the University of Massachusetts Chan Medical School\u2019s expertise on blood stem cell processes, and Caring Cross\u2019s expertise in increasing patient access.<\/p>\n<p>The collaboration will focus on developing a gene-modified stem cell manufacturing process with Trenchant\u2019s AutoCell automated CGT manufacturing platform that is designed to be scalable and operate at place-of-care in an ISO class 7 environment to increase e\ufb03ciencies and decrease costs.<\/p>\n<p>A key reason Trenchant BioSystems\u2019 automated CGT manufacturing platform was selected is its use of a microbubble separation approach as an alternative to immunomagnetic bead-based separation for stem cell gene therapies, point out officials at Caring Cross and Chan Medical School. In addition, AutoCell has a small footprint and significantly fewer facility requirements, important factors for lowering the cost of these therapies, adds Jon Ellis, CEO, Trenchant BioSystems.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A partnership involving a medical school, a non-profit organization, and a biotech company have formed a partnership for the development and manufacture of an accessible and commercially viable hematopoietic stem cell (HSC) manufacturing platform for diseases like sickle cell disease (SCD). The alliance combines Trenchant BioSystems\u2019 technology for automating patient-specific cell and gene therapy (CGT) [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,6],"tags":[],"class_list":["post-234440","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234440","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=234440"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234440\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=234440"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=234440"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=234440"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}