{"id":234221,"date":"2026-03-28T18:06:04","date_gmt":"2026-03-28T23:06:04","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/senescence-at-the-crossroads-of-postpartum-remodeling-and-tumorigenesis"},"modified":"2026-03-28T18:06:04","modified_gmt":"2026-03-28T23:06:04","slug":"senescence-at-the-crossroads-of-postpartum-remodeling-and-tumorigenesis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/senescence-at-the-crossroads-of-postpartum-remodeling-and-tumorigenesis","title":{"rendered":"Senescence at the crossroads of postpartum remodeling and tumorigenesis"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/senescence-at-the-crossroads-of-postpartum-remodeling-and-tumorigenesis.jpg\"><\/a><\/p>\n<p>Cellular senescence has been linked to both beneficial and detrimental functions. Chiche, Djoual, Charifou and colleagues show that senescence supports normal postpartum mammary gland remodeling, but that when oncogenic events coincide with involution, senescent cells enhance tumorigenesis by regulating plasticity, invasion and metastasis.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cellular senescence has been linked to both beneficial and detrimental functions. Chiche, Djoual, Charifou and colleagues show that senescence supports normal postpartum mammary gland remodeling, but that when oncogenic events coincide with involution, senescent cells enhance tumorigenesis by regulating plasticity, invasion and metastasis.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269],"tags":[],"class_list":["post-234221","post","type-post","status-publish","format-standard","hentry","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234221","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=234221"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/234221\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=234221"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=234221"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=234221"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}