{"id":233883,"date":"2026-03-23T06:19:37","date_gmt":"2026-03-23T11:19:37","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/a-lysosome-switch-could-reshape-research-on-cancer-and-neurodegenerative-disease"},"modified":"2026-03-23T06:19:37","modified_gmt":"2026-03-23T11:19:37","slug":"a-lysosome-switch-could-reshape-research-on-cancer-and-neurodegenerative-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/a-lysosome-switch-could-reshape-research-on-cancer-and-neurodegenerative-disease","title":{"rendered":"A lysosome switch could reshape research on cancer and neurodegenerative disease"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-lysosome-switch-could-reshape-research-on-cancer-and-neurodegenerative-disease.jpg\"><\/a><\/p>\n<p>An international research team from Bielefeld University and the Leibniz-Forschungsinstitut f\u00fcr Molekulare Pharmakologie (FMP) has uncovered a previously unknown regulatory mechanism in human cells. For the first time, they demonstrate how a key molecular switch regulates the cell\u2019s \u201crecycling centers.\u201d The findings, published in <a href=\"https:\/\/doi.org\/10.1038\/s41467-026-70345-y\" target=\"_blank\"><i>Nature Communications<\/i><\/a>, provide important insights into the understanding of cancer and neurodegenerative diseases.<\/p>\n<p>Lysosomes are the control centers for the metabolism of cells and tissues, including the brain. They break down defective proteins and other macromolecules into their basic building blocks. At the same time, they determine whether a cell grows or switches into an energy-saving mode. In doing so, they play a key role in health and disease.<\/p>\n<p>A research team led by Prof. Dr. Markus Damme of Bielefeld University and Prof. Volker Haucke, Director of the Leibniz-Forschungsinstitut f\u00fcr Molekulare Pharmakologie (FMP), has now jointly elucidated a key mechanism underlying this regulation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An international research team from Bielefeld University and the Leibniz-Forschungsinstitut f\u00fcr Molekulare Pharmakologie (FMP) has uncovered a previously unknown regulatory mechanism in human cells. For the first time, they demonstrate how a key molecular switch regulates the cell\u2019s \u201crecycling centers.\u201d The findings, published in Nature Communications, provide important insights into the understanding of cancer and [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495,47],"tags":[],"class_list":["post-233883","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233883","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233883"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233883\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233883"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233883"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233883"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}