{"id":233854,"date":"2026-03-22T18:29:47","date_gmt":"2026-03-22T23:29:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/technical-advance-alert-%f0%9f%99%8c"},"modified":"2026-03-22T18:29:47","modified_gmt":"2026-03-22T23:29:47","slug":"technical-advance-alert-%f0%9f%99%8c","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/technical-advance-alert-%f0%9f%99%8c","title":{"rendered":"Technical Advance alert \ud83d\ude4c"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/technical-advance-alert-f09f998c2.jpg\"><\/a><\/p>\n<p><a href=\"https:\/\/doi.org\/10.1172\/jci.insight\">https:\/\/doi.org\/10.1172\/jci.insight<\/a>.<\/p>\n<p>In this Research article, Benjamin D. Philpot &amp; team establish a multimodal dual-reporter mouse that accelerates AngelmanSyndrome therapeutic development through scalable cell-based screening, high-resolution whole-brain mapping, non-invasive live imaging, and sorting neurons with unsilenced paternal Ube3a.<\/p>\n<hr>\n<p>\n<sup>2<\/sup>Animal Models Core.<\/p>\n<p><sup>3<\/sup>Department of Genetics, and.<\/p>\n<p><sup>4<\/sup>Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>https:\/\/doi.org\/10.1172\/jci.insight. In this Research article, Benjamin D. Philpot &amp; team establish a multimodal dual-reporter mouse that accelerates AngelmanSyndrome therapeutic development through scalable cell-based screening, high-resolution whole-brain mapping, non-invasive live imaging, and sorting neurons with unsilenced paternal Ube3a. 2Animal Models Core. 3Department of Genetics, and. 4Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[412,1965,47],"tags":[],"class_list":["post-233854","post","type-post","status-publish","format-standard","hentry","category-genetics","category-mapping","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233854","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233854"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233854\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233854"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233854"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233854"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}