{"id":233753,"date":"2026-03-20T23:53:24","date_gmt":"2026-03-21T04:53:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/ca2-phospholipid-dependent-regulation-of-munc13-1-is-essential-for-post-tetanic-potentiation-at-mossy-fiber-synapses-and-supports-working-memory"},"modified":"2026-03-20T23:53:24","modified_gmt":"2026-03-21T04:53:24","slug":"ca2-phospholipid-dependent-regulation-of-munc13-1-is-essential-for-post-tetanic-potentiation-at-mossy-fiber-synapses-and-supports-working-memory","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/ca2-phospholipid-dependent-regulation-of-munc13-1-is-essential-for-post-tetanic-potentiation-at-mossy-fiber-synapses-and-supports-working-memory","title":{"rendered":"Ca2+-phospholipid-dependent regulation of Munc13-1 is essential for post-tetanic potentiation at mossy fiber synapses and supports working memory"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/ca2-phospholipid-dependent-regulation-of-munc13-1-is-essential-for-post-tetanic-potentiation-at-mossy-fiber-synapses-and-supports-working-memory.gif\"><\/a><\/p>\n<p>L\u00f3pez-Murcia et al. demonstrate that Ca2+-dependent regulation of the vesicle-priming protein Munc13-1 supports synaptic short-term facilitation and post-tetanic potentiation at hippocampal mossy fiber synapses. Disruption of this regulatory mechanism is associated with impaired working memory formation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>L\u00f3pez-Murcia et al. demonstrate that Ca2+-dependent regulation of the vesicle-priming protein Munc13-1 supports synaptic short-term facilitation and post-tetanic potentiation at hippocampal mossy fiber synapses. Disruption of this regulatory mechanism is associated with impaired working memory formation.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-233753","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233753","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233753"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233753\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233753"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233753"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233753"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}