{"id":233734,"date":"2026-03-20T15:11:53","date_gmt":"2026-03-20T20:11:53","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/scientists-discover-on-off-gene-switches-that-could-revolutionize-personalized-medicine"},"modified":"2026-03-20T15:11:53","modified_gmt":"2026-03-20T20:11:53","slug":"scientists-discover-on-off-gene-switches-that-could-revolutionize-personalized-medicine","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/scientists-discover-on-off-gene-switches-that-could-revolutionize-personalized-medicine","title":{"rendered":"Scientists discover on\/off gene switches that could revolutionize personalized medicine"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-discover-on-off-gene-switches-that-could-revolutionize-personalized-medicine.jpg\"><\/a><\/p>\n<p>Year 2025 This could essentially end disease where the diseases would be edited off and the host repaired internally.<\/p>\n<hr>\n<p>\n<em><strong>Scientists identified 473 human genes that act as genetic \u201con\/off switches,\u201d shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. <\/strong><\/em><\/p>\n<p>Study: Switch-like gene expression modulates disease risk. Image Credit: gopixa \/ Shutterstock.<\/p>\n<p>In a recent article published in <a href=\"https:\/\/www.nature.com\/articles\/s41467-025-60513-x\" rel=\"noopener\"><strong><em>Nature Communications<\/em><\/strong><\/a>, researchers analyzed methylomes, transcriptomes, and genomes from 943 individuals to characterize and identify genes that exhibit distinct on-off switches and explore their epigenetic and genetic regulation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Year 2025 This could essentially end disease where the diseases would be edited off and the host repaired internally. Scientists identified 473 human genes that act as genetic \u201con\/off switches,\u201d shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. Study: Switch-like gene expression modulates disease risk. Image Credit: gopixa \/ [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-233734","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233734","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233734"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233734\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233734"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233734"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233734"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}