{"id":233637,"date":"2026-03-19T03:33:51","date_gmt":"2026-03-19T08:33:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/glomerular-basement-membrane-structural-integrity-dictates-trans-tissue-deposition-of-laminin-in-the-kidney"},"modified":"2026-03-19T03:33:51","modified_gmt":"2026-03-19T08:33:51","slug":"glomerular-basement-membrane-structural-integrity-dictates-trans-tissue-deposition-of-laminin-in-the-kidney","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/glomerular-basement-membrane-structural-integrity-dictates-trans-tissue-deposition-of-laminin-in-the-kidney","title":{"rendered":"Glomerular basement membrane structural integrity dictates trans-tissue deposition of laminin in the kidney"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/glomerular-basement-membrane-structural-integrity-dictates-trans-tissue-deposition-of-laminin-in-the-kidney2.jpg\"><\/a><\/p>\n<p>Omachi and Lin et al. uncover an unexpected source of ectopic laminin-\u03b12 deposition in the glomerular basement membrane in Alport syndrome. They show that laminin-\u03b12 circulates in blood and deposits according to basement membrane integrity, revealing a trans-tissue route for extracellular matrix deposition in mammals.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Omachi and Lin et al. uncover an unexpected source of ectopic laminin-\u03b12 deposition in the glomerular basement membrane in Alport syndrome. They show that laminin-\u03b12 circulates in blood and deposits according to basement membrane integrity, revealing a trans-tissue route for extracellular matrix deposition in mammals.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-233637","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233637","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233637"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233637\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233637"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233637"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}