{"id":233603,"date":"2026-03-18T23:19:37","date_gmt":"2026-03-19T04:19:37","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/usp10-deubiquitinates-mtx2-to-suppress-cgas-sting-signaling-in-mi"},"modified":"2026-03-18T23:19:37","modified_gmt":"2026-03-19T04:19:37","slug":"usp10-deubiquitinates-mtx2-to-suppress-cgas-sting-signaling-in-mi","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/usp10-deubiquitinates-mtx2-to-suppress-cgas-sting-signaling-in-mi","title":{"rendered":"USP10 Deubiquitinates MTX2 to Suppress cGAS-STING Signaling in MI"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/usp10-deubiquitinates-mtx2-to-suppress-cgas-sting-signaling-in-mi2.jpg\"><\/a><\/p>\n<p>Zhao &amp; colleagues found how a protective protein, USP10, helps limit excessive inflammation after a heart attack, which may open new avenues for treating cardiac injury. Learn more at.<\/p>\n<hr>\n<p>BACKGROUND: Myocardial infarction (MI) results in 3 distinct regions within the left ventricle:<\/p>\n<p>The infarct zone, the border zone (BZ), and the remote zone. A major focus of MI research.<\/p>\n<p>Is investigating the intrinsic mechanisms in the BZ to alleviate myocardial injury.<\/p>\n<p>USP10 (ubiquitin-specific peptidase 10) expression is reduced in BZ cardiomyocytes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zhao &amp; colleagues found how a protective protein, USP10, helps limit excessive inflammation after a heart attack, which may open new avenues for treating cardiac injury. Learn more at. BACKGROUND: Myocardial infarction (MI) results in 3 distinct regions within the left ventricle: The infarct zone, the border zone (BZ), and the remote zone. A major [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-233603","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233603","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233603"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233603\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233603"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233603"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233603"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}