{"id":233558,"date":"2026-03-18T02:34:38","date_gmt":"2026-03-18T07:34:38","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/end-point-based-threshold-for-the-ambulatory-arterial-stiffness-index"},"modified":"2026-03-18T02:34:38","modified_gmt":"2026-03-18T07:34:38","slug":"end-point-based-threshold-for-the-ambulatory-arterial-stiffness-index","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/end-point-based-threshold-for-the-ambulatory-arterial-stiffness-index","title":{"rendered":"End Point\u2013Based Threshold for the Ambulatory Arterial Stiffness Index"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/end-point-based-threshold-for-the-ambulatory-arterial-stiffness-index2.jpg\"><\/a><\/p>\n<p>RESEARCH ARTICLE: End Point\u2013Based Threshold for the Ambulatory Arterial Stiffness Index <a href=\"https:\/\/twitter.com\/jasta49\">@jasta49<\/a> <a href=\"https:\/\/twitter.com\/melgarejo1024\">@melgarejo1024<\/a> <a href=\"https:\/\/twitter.com\/neurociencias\">@neurociencias<\/a> <a href=\"https:\/\/twitter.com\/PPBoggia\">@PPBoggia<\/a><\/p>\n<hr>\n<p>BACKGROUND: The ambulatory arterial stiffness index (AASI) is increasingly used in clinical research and practice. This individual-participant meta-analysis aims to consolidate the prognostic accuracy of AASI in the general population and to derive an end point\u2013based AASI risk threshold. METHODS: In 12 558 individuals enrolled in 14 population studies (48.8% women; mean age, 59.3 years), AASI was derived by regressing 24-hour diastolic on systolic blood pressure (mm Hg\/mm Hg). Using Cox regression, the risk-carrying AASI threshold was established by examining stepwise increasing AASI levels and by determining the AASI level, yielding a 10-year risk similar to an office systolic pressure of 140 mm Hg. RESULTS: Over 10.7 years (median), 3,027 all-cause deaths and 2,183 cardiovascular end points occurred.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>RESEARCH ARTICLE: End Point\u2013Based Threshold for the Ambulatory Arterial Stiffness Index @jasta49 @melgarejo1024 @neurociencias @PPBoggia BACKGROUND: The ambulatory arterial stiffness index (AASI) is increasingly used in clinical research and practice. This individual-participant meta-analysis aims to consolidate the prognostic accuracy of AASI in the general population and to derive an end point\u2013based AASI risk threshold. METHODS: [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-233558","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233558","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233558"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233558\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233558"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233558"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233558"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}