{"id":233237,"date":"2026-03-13T06:06:52","date_gmt":"2026-03-13T11:06:52","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/decoding-tumor-heterogeneity-a-spatially-informed-pan-cancer-analysis-of-the-tumor-microenvironment"},"modified":"2026-03-13T06:06:52","modified_gmt":"2026-03-13T11:06:52","slug":"decoding-tumor-heterogeneity-a-spatially-informed-pan-cancer-analysis-of-the-tumor-microenvironment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/decoding-tumor-heterogeneity-a-spatially-informed-pan-cancer-analysis-of-the-tumor-microenvironment","title":{"rendered":"Decoding tumor heterogeneity: A spatially informed pan-cancer analysis of the tumor microenvironment"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/decoding-tumor-heterogeneity-a-spatially-informed-pan-cancer-analysis-of-the-tumor-microenvironment.jpg\"><\/a><\/p>\n<p>Lodi et al. create a pan-cancer single-cell atlas characterizing immune cell heterogeneity within the tumor microenvironment (TME). They identify 70 shared cell subtypes, some of which are spatially co-localized to form two distinct immune reactive TME hubs. Both hubs associate with improved checkpoint immunotherapy outcome across different cancer types.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lodi et al. create a pan-cancer single-cell atlas characterizing immune cell heterogeneity within the tumor microenvironment (TME). They identify 70 shared cell subtypes, some of which are spatially co-localized to form two distinct immune reactive TME hubs. Both hubs associate with improved checkpoint immunotherapy outcome across different cancer types.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-233237","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233237","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233237"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233237\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233237"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233237"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233237"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}