{"id":233063,"date":"2026-03-11T10:15:12","date_gmt":"2026-03-11T15:15:12","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/should-we-target-the-mitochondria-in-systemic-lupus-erythematosus-sle"},"modified":"2026-03-11T10:15:12","modified_gmt":"2026-03-11T15:15:12","slug":"should-we-target-the-mitochondria-in-systemic-lupus-erythematosus-sle","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/should-we-target-the-mitochondria-in-systemic-lupus-erythematosus-sle","title":{"rendered":"Should we target the mitochondria in systemic lupus erythematosus (SLE)?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/should-we-target-the-mitochondria-in-systemic-lupus-erythematosus-sle.jpg\"><\/a><\/p>\n<p>In this Research Article, Denis Comte &amp; team link defective mitochondrial recycling to impaired natural killer cell function in SLE and identify potential treatments to restore immune balance:<\/p>\n<p>The image shows transmission electron microscopy of an NK cell from a patient with lupus showing mitochondrial structural alterations (false-colored red). Inset: healthy NK cell with preserved mitochondrial ultrastructure.<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Department of Medicine, Division of <i>Immunology<\/i> and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.<\/p>\n<p><sup>2<\/sup>Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.<\/p>\n<p><sup>3<\/sup>Department of Immunobiology, University of Lausanne, Epalinges, Switzerland.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this Research Article, Denis Comte &amp; team link defective mitochondrial recycling to impaired natural killer cell function in SLE and identify potential treatments to restore immune balance: The image shows transmission electron microscopy of an NK cell from a patient with lupus showing mitochondrial structural alterations (false-colored red). Inset: healthy NK cell with preserved [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-233063","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233063","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233063"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233063\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233063"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233063"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233063"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}