{"id":233043,"date":"2026-03-11T05:50:09","date_gmt":"2026-03-11T10:50:09","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/pv-inhibitory-neurons-not-overall-prefrontal-cortex-decline-linked-to-cocaine-seeking-relapse"},"modified":"2026-03-11T05:50:09","modified_gmt":"2026-03-11T10:50:09","slug":"pv-inhibitory-neurons-not-overall-prefrontal-cortex-decline-linked-to-cocaine-seeking-relapse","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/pv-inhibitory-neurons-not-overall-prefrontal-cortex-decline-linked-to-cocaine-seeking-relapse","title":{"rendered":"PV inhibitory neurons, not overall prefrontal cortex decline, linked to cocaine-seeking relapse"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/pv-inhibitory-neurons-not-overall-prefrontal-cortex-decline-linked-to-cocaine-seeking-relapse2.jpg\"><\/a><\/p>\n<p>Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline in the function of the prefrontal cortex (PFC), which regulates impulses. However, a joint international research team has recently revealed that the cause of addiction relapse is not a simple decline in brain function, but rather an imbalance in specific neural circuits.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline in the function of the prefrontal cortex (PFC), which regulates impulses. However, a joint international research team has recently revealed that the cause [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-233043","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233043","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=233043"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/233043\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=233043"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=233043"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=233043"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}