{"id":232892,"date":"2026-03-09T23:17:28","date_gmt":"2026-03-10T04:17:28","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/circulating-malat1-in-preeclampsia-and-association-with-cardiometabolic-risk"},"modified":"2026-03-09T23:17:28","modified_gmt":"2026-03-10T04:17:28","slug":"circulating-malat1-in-preeclampsia-and-association-with-cardiometabolic-risk","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/circulating-malat1-in-preeclampsia-and-association-with-cardiometabolic-risk","title":{"rendered":"Circulating MALAT1 in Preeclampsia and Association With Cardiometabolic Risk"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/circulating-malat1-in-preeclampsia-and-association-with-cardiometabolic-risk2.jpg\"><\/a><\/p>\n<p>RESEARCH ARTICLE: Circulating <i>MALAT1<\/i> in Preeclampsia and Association With Cardiometabolic Risk <a href=\"https:\/\/twitter.com\/tovelekva\">@tovelekva<\/a><\/p>\n<hr>\n<p>BACKGROUND: Preeclampsia is a hypertensive disorder affecting 2% to 8% of pregnancies. Women with a history of preeclampsia have an increased risk of cardiovascular disease. The long noncoding RNA <i>MALAT1<\/i> is shown to regulate inflammatory responses linked to cardiovascular disease. <i>MALAT1<\/i> is decreased in preeclampsia placentas and may have a cis-regulatory function on neighboring RNAs. METHODS: Expression of <i>MALAT1<\/i>, NEAT1, <i>mascRNA<\/i>, SCYL1, and FRMD8 was assessed in peripheral blood mononuclear cells, and <i>MALAT1<\/i> in plasma and extracellular vesicles, at 22 to 24 and 36 to 38 weeks of gestation in healthy (n=214) and preeclampsia (n=37) women from the STORK cohort study (STORe barn og Komplikasjoner, translated as Large Babies and Complications) and at 5-year follow-up in women with and without history of preeclampsia (n=29; n=271).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>RESEARCH ARTICLE: Circulating MALAT1 in Preeclampsia and Association With Cardiometabolic Risk @tovelekva BACKGROUND: Preeclampsia is a hypertensive disorder affecting 2% to 8% of pregnancies. Women with a history of preeclampsia have an increased risk of cardiovascular disease. The long noncoding RNA MALAT1 is shown to regulate inflammatory responses linked to cardiovascular disease. MALAT1 is decreased [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-232892","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232892"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232892\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232892"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232892"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}