{"id":232872,"date":"2026-03-09T15:09:30","date_gmt":"2026-03-09T20:09:30","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/cancer-drug-reduces-early-alzheimers-like-brain-hyperconnectivity-in-lab-tests"},"modified":"2026-03-09T15:09:30","modified_gmt":"2026-03-09T20:09:30","slug":"cancer-drug-reduces-early-alzheimers-like-brain-hyperconnectivity-in-lab-tests","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/cancer-drug-reduces-early-alzheimers-like-brain-hyperconnectivity-in-lab-tests","title":{"rendered":"Cancer drug reduces early Alzheimer\u2019s-like brain hyperconnectivity in lab tests"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/cancer-drug-reduces-early-alzheimers-like-brain-hyperconnectivity-in-lab-tests3.jpg\"><\/a><\/p>\n<p>Neuroscientists at King\u2019s College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer\u2019s disease. <a href=\"https:\/\/www.nature.com\/articles\/s41398-026-03905-x\" target=\"_blank\">Published<\/a> in <i>Translational Psychiatry<\/i>, the study also demonstrated that a cancer medication has the potential to reduce this hyperconnectivity.<\/p>\n<p>The research showed that low levels of the protein <a href=\"https:\/\/medicalxpress.com\/news\/2024-09-multiple-dementia-factors-greater-chance.html?utm_source=embeddings&utm_medium=related&utm_campaign=internal\" rel=\"related\">amyloid-beta<\/a> could induce hyperconnectivity and this pattern closely resembled changes seen in the brains of people with mild cognitive impairment (MCI). Amyloid-beta is thought to be instrumental in Alzheimer\u2019s disease, where it creates plaques\u2014or sticky clumps of amyloid-beta proteins\u2014around the neurons.<\/p>\n<p>These new findings suggest that low levels of amyloid-beta alone are enough to trigger early, disease-relevant changes in how brain cells connect.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neuroscientists at King\u2019s College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer\u2019s disease. Published in Translational Psychiatry, the study also demonstrated that a cancer medication has the potential to reduce this hyperconnectivity. The research showed that low levels of the protein amyloid-beta could induce hyperconnectivity [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-232872","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232872","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232872"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232872\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232872"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232872"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232872"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}