{"id":232741,"date":"2026-03-07T03:49:29","date_gmt":"2026-03-07T09:49:29","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/rab3gap2-is-a-regulator-of-skeletal-muscle-endothelial-cell-proliferation-and-associated-with-capillary-to-fiber-ratio"},"modified":"2026-03-07T03:49:29","modified_gmt":"2026-03-07T09:49:29","slug":"rab3gap2-is-a-regulator-of-skeletal-muscle-endothelial-cell-proliferation-and-associated-with-capillary-to-fiber-ratio","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/rab3gap2-is-a-regulator-of-skeletal-muscle-endothelial-cell-proliferation-and-associated-with-capillary-to-fiber-ratio","title":{"rendered":"RAB3GAP2 is a regulator of skeletal muscle endothelial cell proliferation and associated with capillary-to-fiber ratio"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/rab3gap2-is-a-regulator-of-skeletal-muscle-endothelial-cell-proliferation-and-associated-with-capillary-to-fiber-ratio2.jpg\"><\/a><\/p>\n<p>Str\u00f6m et al. identify the rs115660502 variant in <i>RAB3GAP2<\/i> associated with increased skeletal muscle capillary-to-fiber ratio and enriched in endurance athletes. This variant reduces <i>RAB3GAP2<\/i> expression, enhancing endothelial proliferation, tube formation, and TNC secretion, thereby promoting exercise-like angiogenesis and microvascular remodeling in skeletal muscle.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Str\u00f6m et al. identify the rs115660502 variant in RAB3GAP2 associated with increased skeletal muscle capillary-to-fiber ratio and enriched in endurance athletes. This variant reduces RAB3GAP2 expression, enhancing endothelial proliferation, tube formation, and TNC secretion, thereby promoting exercise-like angiogenesis and microvascular remodeling in skeletal muscle.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-232741","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232741","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232741"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232741\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232741"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232741"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232741"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}