{"id":232713,"date":"2026-03-06T22:09:18","date_gmt":"2026-03-07T04:09:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/a-bicistronic-viral-genome-uses-a-compact-type-iv-ires-near-its-3%e2%80%b2-end-to-express-a-transmembrane-protein"},"modified":"2026-03-06T22:09:18","modified_gmt":"2026-03-07T04:09:18","slug":"a-bicistronic-viral-genome-uses-a-compact-type-iv-ires-near-its-3%e2%80%b2-end-to-express-a-transmembrane-protein","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/a-bicistronic-viral-genome-uses-a-compact-type-iv-ires-near-its-3%e2%80%b2-end-to-express-a-transmembrane-protein","title":{"rendered":"A bicistronic viral genome uses a compact type IV IRES near its 3\u2032 end to express a transmembrane protein"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-bicistronic-viral-genome-uses-a-compact-type-iv-ires-near-its-3e280b2-end-to-express-a-transmembrane-protein2.jpg\"><\/a><\/p>\n<p>Sherlock et al. examine an IRES RNA that initiates translation of a small <i>downstream<\/i> coding region within a viral genome. The structure, function, and mechanism of this IRES are interrogated experimentally. Differential translation efficiencies between two IRESs within one viral genome exemplify RNA-structure-based tuning of gene expression.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sherlock et al. examine an IRES RNA that initiates translation of a small downstream coding region within a viral genome. The structure, function, and mechanism of this IRES are interrogated experimentally. Differential translation efficiencies between two IRESs within one viral genome exemplify RNA-structure-based tuning of gene expression.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-232713","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232713","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232713"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232713\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}