{"id":232496,"date":"2026-03-03T21:07:33","date_gmt":"2026-03-04T03:07:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/does-this-ed-drug-harm-the-retina"},"modified":"2026-03-03T21:07:33","modified_gmt":"2026-03-04T03:07:33","slug":"does-this-ed-drug-harm-the-retina","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/does-this-ed-drug-harm-the-retina","title":{"rendered":"Does This ED Drug Harm the Retina?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/does-this-ed-drug-harm-the-retina.jpg\"><\/a><\/p>\n<p>Men with erectile dysfunction (ED) who used sildenafil had a higher risk for serous retinal detachment than those who did not use the drug, a new study finds.<\/p>\n<p>\u201cOur results extend prior claims-based signals of an association between\u201d phosphodiesterase type 5 (PDE5) inhibitors and serous retinal detachment, the researchers reported.<\/p>\n<hr>\n<p>The absence of associations with retinal vascular occlusion and ischemic optic neuropathy suggest sildenafil\u2019s ocular risks may be specific to serous retinal pathology rather than ischemic events affecting the vessels or optic nerve, they wrote.<\/p>\n<p>The study was led by Jaffer Shah of Weill Cornell Medicine in New York City. It was published <a href=\"https:\/\/www.nature.com\/articles\/s41433-026-04326-2\" rel=\"nofollow\" target=\"_blank\">online<\/a> on February 21 in <em>Eye<\/em>.<\/p>\n<p>The use of electronic health records may have introduced residual confounding and misclassification of the use of sildenafil.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Men with erectile dysfunction (ED) who used sildenafil had a higher risk for serous retinal detachment than those who did not use the drug, a new study finds. \u201cOur results extend prior claims-based signals of an association between\u201d phosphodiesterase type 5 (PDE5) inhibitors and serous retinal detachment, the researchers reported. The absence of associations with [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-232496","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232496","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232496"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232496\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232496"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232496"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232496"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}