{"id":232405,"date":"2026-03-02T17:06:38","date_gmt":"2026-03-02T23:06:38","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/a-new-class-of-alzheimers-biomarkers-why-protein-shape-may-beat-protein-levels"},"modified":"2026-03-02T17:06:38","modified_gmt":"2026-03-02T23:06:38","slug":"a-new-class-of-alzheimers-biomarkers-why-protein-shape-may-beat-protein-levels","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/a-new-class-of-alzheimers-biomarkers-why-protein-shape-may-beat-protein-levels","title":{"rendered":"A new class of Alzheimer\u2019s biomarkers: Why protein shape may beat protein levels"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-new-class-of-alzheimers-biomarkers-why-protein-shape-may-beat-protein-levels2.jpg\"><\/a><\/p>\n<p>Researchers have identified a new type of blood-based biomarker test for Alzheimer\u2019s disease that measures structural changes in proteins, providing more information on the underlying biology of the disease than standard blood tests. <a href=\"https:\/\/www.nature.com\/articles\/s43587-026-01078-2\" target=\"_blank\">The findings,<\/a> published in <i>Nature Aging<\/i>, also provide new insights into how Alzheimer\u2019s disease biology may differ between males and females.<\/p>\n<p>\u201cThis work introduces a fundamentally new, blood-based approach to detecting and staging Alzheimer\u2019s disease,\u201d said Dr. Richard Hodes, director of NIH\u2019s National Institute on Aging (NIA). \u201cBy revealing protein structural changes associated with genetic risk, symptom severity, and sex differences\u2014features not captured by existing biomarkers\u2014this research could enable earlier diagnosis and more effective clinical trials.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have identified a new type of blood-based biomarker test for Alzheimer\u2019s disease that measures structural changes in proteins, providing more information on the underlying biology of the disease than standard blood tests. The findings, published in Nature Aging, also provide new insights into how Alzheimer\u2019s disease biology may differ between males and females. \u201cThis [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269,47,1901],"tags":[],"class_list":["post-232405","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension","category-neuroscience","category-sex"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232405","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232405"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232405\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232405"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232405"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232405"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}