{"id":232381,"date":"2026-03-02T09:22:14","date_gmt":"2026-03-02T15:22:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/abstract-in-the-1960s-megamitochondria-in-hepatocytes-were-identified-in-injured-liver-tissue"},"modified":"2026-03-02T09:22:14","modified_gmt":"2026-03-02T15:22:14","slug":"abstract-in-the-1960s-megamitochondria-in-hepatocytes-were-identified-in-injured-liver-tissue","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/abstract-in-the-1960s-megamitochondria-in-hepatocytes-were-identified-in-injured-liver-tissue","title":{"rendered":"Abstract: In the 1960\u2019s, megamitochondria in hepatocytes were identified in injured liver tissue"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/abstract86.jpg\"><\/a><\/p>\n<p>Here, Wen-Xing Ding find alterations in mitochondrial dynamics and the accumulation of large mitochondria contribute to liver tumor development in mice: <a href=\"https:\/\/doi.org\/10.1172\/JCI194441\">https:\/\/doi.org\/10.1172\/JCI194441<\/a> # MASH<\/p>\n<p>The EM image shows liver cells with megamitochondria (arrows) from mice lacking liver-specific dynamin-related protein 1 (Dnm1).<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.<\/p>\n<p><sup>2<\/sup>Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences and.<\/p>\n<p><sup>3<\/sup>Department of Pharmacology, School of Medicine, Wayne State University, Detroit, Michigan, USA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here, Wen-Xing Ding find alterations in mitochondrial dynamics and the accumulation of large mitochondria contribute to liver tumor development in mice: https:\/\/doi.org\/10.1172\/JCI194441 # MASH The EM image shows liver cells with megamitochondria (arrows) from mice lacking liver-specific dynamin-related protein 1 (Dnm1). 1Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-232381","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232381"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232381\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}