{"id":232379,"date":"2026-03-02T09:18:34","date_gmt":"2026-03-02T15:18:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/03\/attenuating-age-related-decline-in-dendritic-cell-migration-improves-vaccine-efficacy-via-gut-immune-crosstalk"},"modified":"2026-03-02T09:18:34","modified_gmt":"2026-03-02T15:18:34","slug":"attenuating-age-related-decline-in-dendritic-cell-migration-improves-vaccine-efficacy-via-gut-immune-crosstalk","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/03\/attenuating-age-related-decline-in-dendritic-cell-migration-improves-vaccine-efficacy-via-gut-immune-crosstalk","title":{"rendered":"Attenuating age-related decline in dendritic cell migration improves vaccine efficacy via gut-immune crosstalk"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/attenuating-age-related-decline-in-dendritic-cell-migration-improves-vaccine-efficacy-via-gut-immune-crosstalk.jpg\"><\/a><\/p>\n<p>Dai and colleagues implicate defective dendritic cell migration in impaired vaccine responses in aged mice. Oral delivery of yeast-derived nanoparticles promotes migration of dendritic cells from the gut to lymph nodes and restores vaccine efficacy in aged mice.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dai and colleagues implicate defective dendritic cell migration in impaired vaccine responses in aged mice. Oral delivery of yeast-derived nanoparticles promotes migration of dendritic cells from the gut to lymph nodes and restores vaccine efficacy in aged mice.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,4],"tags":[],"class_list":["post-232379","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232379"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232379\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232379"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232379"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}