{"id":232223,"date":"2026-02-27T13:06:37","date_gmt":"2026-02-27T19:06:37","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/study-suggests-protein-made-in-the-liver-is-a-key-factor-in-mens-bone-health"},"modified":"2026-02-27T13:06:37","modified_gmt":"2026-02-27T19:06:37","slug":"study-suggests-protein-made-in-the-liver-is-a-key-factor-in-mens-bone-health","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/study-suggests-protein-made-in-the-liver-is-a-key-factor-in-mens-bone-health","title":{"rendered":"Study suggests protein made in the liver is a key factor in men\u2019s bone health"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/study-suggests-protein-made-in-the-liver-is-a-key-factor-in-mens-bone-health2.jpg\"><\/a><\/p>\n<p>New research suggests the liver plays a previously unrecognized role in bone health, but only in males. A McGill University-led study published in Matrix Biology found that a protein made in the liver helps regulate bone growth in male mice, but not in females. The findings may help explain why men with liver disease are more likely to experience bone loss.<\/p>\n<p>The protein, known as plasma fibronectin, is naturally present in blood at higher levels in men than in women, declines when the liver is damaged and builds up in bone to modulate bone formation. This suggests men rely more heavily on the protein to maintain bone strength than do women.<\/p>\n<p>\u201cAbout 60% of osteoporosis cases in men are secondary to other underlying health conditions,\u201d said senior author Mari Tuulia Kaartinen, Associate Professor in McGill\u2019s Faculty of Dental Medicine and Oral Health Sciences. \u201cOur findings suggest this protein may be one of the biological links connecting liver disease to bone loss.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New research suggests the liver plays a previously unrecognized role in bone health, but only in males. A McGill University-led study published in Matrix Biology found that a protein made in the liver helps regulate bone growth in male mice, but not in females. The findings may help explain why men with liver disease are [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-232223","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232223","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232223"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232223\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232223"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232223"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232223"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}