{"id":232178,"date":"2026-02-27T01:19:57","date_gmt":"2026-02-27T07:19:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/degs1-related-hypomyelinating-leukodystrophyfour-individuals-from-same-family-and-review-of-literature"},"modified":"2026-02-27T01:19:57","modified_gmt":"2026-02-27T07:19:57","slug":"degs1-related-hypomyelinating-leukodystrophyfour-individuals-from-same-family-and-review-of-literature","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/degs1-related-hypomyelinating-leukodystrophyfour-individuals-from-same-family-and-review-of-literature","title":{"rendered":"DEGS1-Related Hypomyelinating LeukodystrophyFour Individuals From Same Family and Review of Literature"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/degs1-related-hypomyelinating-leukodystrophyfour-individuals-from-same-family-and-review-of-literature2.jpg\"><\/a><\/p>\n<p>Degs1-related hypomyelinating leukodystrophy: four individuals from same family and review of literature.<\/p>\n<hr>\n<p>ObjectivesDEGS1-related leukodystrophy has been described in 33 individuals to date with varying degrees of neurologic symptoms and atrophy\/hypomyelination on MRI brain. We describe a family of 4 individuals with DEGS1-related leukodystrophy with phenotypic heterogeneity both within the family and in previously reported individuals.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Degs1-related hypomyelinating leukodystrophy: four individuals from same family and review of literature. ObjectivesDEGS1-related leukodystrophy has been described in 33 individuals to date with varying degrees of neurologic symptoms and atrophy\/hypomyelination on MRI brain. We describe a family of 4 individuals with DEGS1-related leukodystrophy with phenotypic heterogeneity both within the family and in previously reported individuals.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-232178","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232178","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232178"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232178\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232178"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232178"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232178"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}