{"id":232116,"date":"2026-02-26T01:14:47","date_gmt":"2026-02-26T07:14:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/spatiotemporal-coordination-of-slit-robo-repulsion-and-neurturin-gfr%ce%b1-attraction-guides-multipolar-migration-during-retinal-lamination"},"modified":"2026-02-26T01:14:47","modified_gmt":"2026-02-26T07:14:47","slug":"spatiotemporal-coordination-of-slit-robo-repulsion-and-neurturin-gfr%ce%b1-attraction-guides-multipolar-migration-during-retinal-lamination","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/spatiotemporal-coordination-of-slit-robo-repulsion-and-neurturin-gfr%ce%b1-attraction-guides-multipolar-migration-during-retinal-lamination","title":{"rendered":"Spatiotemporal coordination of Slit-Robo repulsion and neurturin-Gfr\u03b1 attraction guides multipolar migration during retinal lamination"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/spatiotemporal-coordination-of-slit-robo-repulsion-and-neurturin-gfrceb1-attraction-guides-multipolar-migration-during-retinal-lamination2.jpg\"><\/a><\/p>\n<p>Lehtim\u00e4ki et al. reveal how repulsive Slit1b\/2-Robo2 and attractive neurturin-Gfr\u03b11\/2-Ret signaling jointly coordinate multipolar migration of horizontal cells through crowded, scaffold-free environments of the vertebrate retina. This work was enabled by sophisticated transcriptomics analysis, targeted F0 CRISPR screening, and 3D fixed and live imaging.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lehtim\u00e4ki et al. reveal how repulsive Slit1b\/2-Robo2 and attractive neurturin-Gfr\u03b11\/2-Ret signaling jointly coordinate multipolar migration of horizontal cells through crowded, scaffold-free environments of the vertebrate retina. This work was enabled by sophisticated transcriptomics analysis, targeted F0 CRISPR screening, and 3D fixed and live imaging.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-232116","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232116","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232116"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232116\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232116"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232116"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232116"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}