{"id":232000,"date":"2026-02-24T17:06:58","date_gmt":"2026-02-24T23:06:58","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/abstract-birt-hogg-dube-syndrome-is-largely-characterized-by-pulmonary-cysts-but-disease-models-for-this-lung-phenotype-are-lacking"},"modified":"2026-02-24T17:06:58","modified_gmt":"2026-02-24T23:06:58","slug":"abstract-birt-hogg-dube-syndrome-is-largely-characterized-by-pulmonary-cysts-but-disease-models-for-this-lung-phenotype-are-lacking","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/abstract-birt-hogg-dube-syndrome-is-largely-characterized-by-pulmonary-cysts-but-disease-models-for-this-lung-phenotype-are-lacking","title":{"rendered":"Abstract: Birt-Hogg-Dub\u00e9 syndrome is largely characterized by pulmonary cysts, but disease models for this lung phenotype are lacking"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/abstract80.jpg\"><\/a><\/p>\n<p>Here, Elizabeth P. Henske report mTORC1 hyperactivation in cystic lungs from patients and validate its role in lung cyst formation using a novel pre-clinical model:<\/p>\n<p>The figure shows lung mesenchymal and epithelial cell differentiation.<\/p>\n<hr>\n<p>\n<sup>1<\/sup>Division of Pulmonary, Critical Care and Sleep Medicine; Department of Internal Medicine; University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.<\/p>\n<p><sup>2<\/sup>The Saban Research Institute, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.<\/p>\n<p><sup>3<\/sup>Division of Pulmonary and Critical Care Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts, USA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here, Elizabeth P. Henske report mTORC1 hyperactivation in cystic lungs from patients and validate its role in lung cyst formation using a novel pre-clinical model: The figure shows lung mesenchymal and epithelial cell differentiation. 1Division of Pulmonary, Critical Care and Sleep Medicine; Department of Internal Medicine; University of Cincinnati College of Medicine, Cincinnati, Ohio, USA. [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-232000","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232000","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=232000"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/232000\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=232000"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=232000"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=232000"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}