{"id":231980,"date":"2026-02-24T06:08:34","date_gmt":"2026-02-24T12:08:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/abstract-opening-the-gates-to-the-blood-brain-barrier-bbb-in-a-high-grade-glioma-model"},"modified":"2026-02-24T06:08:34","modified_gmt":"2026-02-24T12:08:34","slug":"abstract-opening-the-gates-to-the-blood-brain-barrier-bbb-in-a-high-grade-glioma-model","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/abstract-opening-the-gates-to-the-blood-brain-barrier-bbb-in-a-high-grade-glioma-model","title":{"rendered":"Abstract: Opening the gates to the blood brain barrier (BBB) in a high-grade glioma model"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/abstract75.jpg\"><\/a><\/p>\n<p>Amy B. Heimberger find therapeutic benefit in adding the STING agonist 8,803 to radiation in preclinical models of glioma. The combination reprogramed the glioma tumor microenvironment, and 8,803 induced the opening of the blood-brain barrier.<\/p>\n<hr>\n<p>\n<sup>3<\/sup>Department of Radiology.<\/p>\n<p><sup>4<\/sup>Department of Neurology, and.<\/p>\n<p><sup>5<\/sup>Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Amy B. Heimberger find therapeutic benefit in adding the STING agonist 8,803 to radiation in preclinical models of glioma. The combination reprogramed the glioma tumor microenvironment, and 8,803 induced the opening of the blood-brain barrier. 3Department of Radiology. 4Department of Neurology, and. 5Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-231980","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231980","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=231980"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231980\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=231980"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=231980"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=231980"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}