{"id":231626,"date":"2026-02-19T10:09:02","date_gmt":"2026-02-19T16:09:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/deep-characterization-of-refractory-epilepsy-due-to-mild-malformation-of-cortical-development-with-oligodendroglial-hyperplasia-moghe-and-insights-into-the-role-of-invasive-monitoring"},"modified":"2026-02-19T10:09:02","modified_gmt":"2026-02-19T16:09:02","slug":"deep-characterization-of-refractory-epilepsy-due-to-mild-malformation-of-cortical-development-with-oligodendroglial-hyperplasia-moghe-and-insights-into-the-role-of-invasive-monitoring","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/deep-characterization-of-refractory-epilepsy-due-to-mild-malformation-of-cortical-development-with-oligodendroglial-hyperplasia-moghe-and-insights-into-the-role-of-invasive-monitoring","title":{"rendered":"Deep characterization of refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) and insights into the role of invasive monitoring"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/deep-characterization-of-refractory-epilepsy-due-to-mild-malformation-of-cortical-development-with-oligodendroglial-hyperplasia-moghe-and-insights-into-the-role-of-invasive-monitoring2.jpg\"><\/a><\/p>\n<p>This study provides detailed electro-clinical characterization of surgically treated MOGHE patients and highlights the impact of SEEG on their outcome.<\/p>\n<hr>\n<p>Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of the epileptogenic zone, which can be challenging due to the subtle imaging features. The aim of this project was to provide an in-depth electro-clinical characterization of MOGHE in patients with medically intractable epilepsy, and to assess the role of stereo-electroencephalography (SEEG) in tailoring the resection and optimizing surgical outcome.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This study provides detailed electro-clinical characterization of surgically treated MOGHE patients and highlights the impact of SEEG on their outcome. Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-231626","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231626","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=231626"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231626\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=231626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=231626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=231626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}