{"id":231612,"date":"2026-02-19T02:12:51","date_gmt":"2026-02-19T08:12:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2026\/02\/immunoglobulin-a-producing-cells-mediate-the-clinical-benefits-of-metformin-via-interleukin-10"},"modified":"2026-02-19T02:12:51","modified_gmt":"2026-02-19T08:12:51","slug":"immunoglobulin-a-producing-cells-mediate-the-clinical-benefits-of-metformin-via-interleukin-10","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2026\/02\/immunoglobulin-a-producing-cells-mediate-the-clinical-benefits-of-metformin-via-interleukin-10","title":{"rendered":"Immunoglobulin A-producing cells mediate the clinical benefits of metformin via interleukin-10"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/immunoglobulin-a-producing-cells-mediate-the-clinical-benefits-of-metformin-via-interleukin-102.jpg\"><\/a><\/p>\n<p>Guo et al. show that metformin enhances intestinal IgA immunity via gut microbiota and increases gut antigen-specific IgA-producing IL-10+ cells in the liver and VAT. IL-10 from these cells mediates the clinical benefits of metformin.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Guo et al. show that metformin enhances intestinal IgA immunity via gut microbiota and increases gut antigen-specific IgA-producing IL-10+ cells in the liver and VAT. IL-10 from these cells mediates the clinical benefits of metformin.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-231612","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231612","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=231612"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/231612\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=231612"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=231612"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=231612"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}